Tex Heart Inst J. 2009;36(2):104-10.

Quality of life after replacement of the ascending aorta in patients with true aneurysms.
Lohse F, Lang N, Schiller W, Roell W, Dewald O, Preusse CJ, Welz A, Schmitz C.

Department of Cardiac Surgery, University of Bonn, Germany.

True aneurysms of the ascending aorta often remain undetected, yet their sequelae carry a high rate of mortality and morbidity. The operative risk of nonemergent replacement of the ascending aorta is low. It is important to consider quality of life in determining the most appropriate treatment for patients who have aneurysms but have not yet experienced major complications.From January 1999 to December 2003, 134 consecutive patients underwent replacement of a dilated ascending aorta at our center.

Another 124 patients with acute or chronic aortic dissections, aortic rupture, or intramural hematoma were excluded. Standard SF-36 and general health questionnaires were sent to all 124 survivors who could be traced. Follow-up was 98.4% complete.

The mean age of the survivors was 61.7 +/- 11 years, and 63.4% were men. Operative procedures consisted of supracoronary replacement of the ascending aorta in 35.9%, the Wheat procedure in 44%, the David procedure in 11.2%, the Bentall-DeBono procedure in 9%, and the Cabrol procedure in 2.2%. Patients were monitored until May 2005.Thirty-day and midterm mortality rates were 3.7% and 3.9%, respectively. Morbidity due to stroke was 6%, to bleeding 6%, and to myocardial infarction 4.4%. Postoperative quality-of-life evaluation revealed many subscales of SF-36 that were below the norm when compared with a standard population in physically dominated categories.

Replacement of the dilated ascending aorta carries acceptable risk in regard to operative death and postoperative quality of life, although this last showed some decline in comparison with quality of life in a normal, healthy population.

PMID: 19436802 [PubMed – indexed for MEDLINE]PMCID: PMC2676602Free PMC Article
source: http://www.ncbi.nlm.nih.gov/pubmed/19436802